What is the study about?
This study is investigating whether measurements of the eye can be used with other tests to detect dementia earlier. By comparing the results of non-invasive tests similar to those done in an eye doctor’s office with established tests of cognition, magnetic resonance imaging (MRI) and a positron emission tomography (PET) scan, researchers can look for links between changes in parts of the eye in dementia.
TDRA sites
- Sunnybrook Health Sciences Centre, Bayview Campus (2075 Bayview Avenue, Toronto, Ontario)
- CAMH (1001 Queen Street West, Toronto, Ontario)
- St. Michael’s Hospital (30 Bond Street, Toronto, Ontario)
- Toronto Western Hospital (399 Bathurst St., Toronto, Ontario)
- Baycrest (3560 Bathurst Street, Toronto, Ontario)
Eligibility: Who can participate?
Participants must be:
- 50-90 years of age or older
- Have a diagnosis of Alzheimer’s disease, mild cognitive impairment (MCI), or vascular cognitive impairment (VCI), Lewy Body Spectrum disorders, or be a healthy volunteer
Time requirement
4-5 visits over 4 months. The visits will include undergoing brain imaging (MRI, PET), cognitive testing, gait and balance assessments, eye-imaging, cognitive and functional questionnaires, and taking blood samples.
TDRA study investigator
Drs. Sandra Black, Sanjeev Kumar, Corinne Fischer, Howard Chertkow and Carmela Tartaglia
Contact
To learn more about the study or find out how to join, please contact the CAMH Geriatric Mental Health Research team:
- Phone: (416) 583-1350
- Email: research.gmhs@camh.ca
More information
Click here to learn more about this study: https://clinicaltrials.gov/ct2/show/NCT02524405