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Dr. John B. Vincent

​Molecular Neuropsychiatry and Development Laboratory
Centre for Addiction and Mental Health
250 College Street, R601/602
Toronto, Ontario M5S 2S1
(416) 535-8501 ext. 6487
john.vincent@camh.ca​

Dr. John Vincent is a Senior Scientist and Head of the Molecular Neuropsychiatry and Development Laboratory of the Psychiatric Neurogenetics Section in the Neuroscience Research Department, and an Associate Scientist of The Centre for Applied Genomics at The Hospital for Sick Children, Toronto. He is an Associate Professor in the Child and Family Program with the Department of Psychiatry at the University of Toronto.

Areas of Research
Dr. Vincent’s research is focused on providing a better understanding of the genetics and molecular pathways involved with autism and other developmental and intellectual disability disorders such as Rett syndrome. His work includes genetic mapping for autism on the X-chromosome, including studies of a type of mutation called copy number variants. This work has identified a number of genes that are associated with autism, including the PTCHD1 gene. In addition, he was involved in the discovery of a new variant of the Rett syndrome gene. This finding sparked the discovery of disease-causing mutations for a number of Rett syndrome patients, for whom no mutation could previously be found. Dr. Vincent’s studies have also recently discovered several new genes involved in intellectual disability. This work was done by mapping regions at risk in affected families from Pakistan, where marriage between cousins is common and multiple family members can be affected. The discoveries include a new gene for Joubert syndrome, CC2D2A, and a new gene for a type of mental retardation, TRAPPC9, inherited through recessive genes. He is also involved in a study searching for genes related to bipolar affective disorder. For more information, visit Dr. Vincent's personal website.
 
Publications
View Dr. Vincent's publications on PubMed.

 

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