Mood and Anxiety Disorders Program
Centre for Addiction and Mental Health
250 College Street
Toronto, Ontario M5T1R8
(416) 535-8501 ext. 6856
Dr. Zindel Segal is Head of the Cognitive Behaviour Therapy Clinic of the Mood and Anxiety Disorders Program in the Clinical Research Department. He is a Professor in the Departments of Psychiatry and Psychology at the University of Toronto.
Areas of Research
Dr. Segal’s research is aimed at understanding the nature of vulnerability to depression relapse for individuals in remission. Over the past eight years, he has participated in the development and evaluation of Mindfulness-Based Cognitive Therapy which integrates elements of Cognitive Behaviour Therapy (CBT) with mindfulness meditation enabling patients to catch the triggers much sooner and prevent a cycle of relapse from developing. Dr. Segal and his colleagues have used PET-imaging to demonstrate the differential effect of CBT vs. antidepressants on key brain pathways fundamental to depression. He has also developed a highly novel mood induction paradigm that demonstrates which patients are most likely to relapse after successful treatment with either CBT or medications.
View Dr. Segal's publications on PubMed.