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Alcohol Research

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Why is this important ?

Alcohol is the cause of tremendous impact on individuals and society. There are a greater number of Canadians drinking at hazardous levels as well as a greater alcohol-related mortality compared to a decade earlier, with the societal cost of alcohol abuse noted to be $14.6 billion in 2002.
 

Our Discoveries

Following up on our successful strategy that led to multiple discoveries in the field of nicotine addiction, we are currently exploring if those targets could also be successful targets for alcohol addiction. For this purpose, we have implemented state-of-the-art methods to study alcohol addiction in preclinical models.
 
We are exploring the brain of research participants with alcohol problems using Positron Emission Tomography approaches and we are collaborating with Dr. Z. Jeff Daskalakis to measure cortical excitability following alcohol administration.  
 

Clinical Impact

Improving access to pharmacotherapies: As part of the Addiction Medicine Service of the Centre for Addiction and Mental Health, the Alcohol Research and Treatment Clinic (ARTC) brings together an inter-professional team of physicians, nurses and specialized therapists to improve access to pharmacotherapies for the treatment of alcohol dependence. Led by Dr. Bernard Le Foll, the clinic also includes research and evaluation components to find new evidence-based treatment strategies that will inform delivery of care at CAMH, throughout the province and beyond.
 
We have changed the way clinical care is provided at CAMH around alcohol dependence by providing access to various approved pharmacotherapies (disulfiram, naltrexone and acamprosate) and second lines therapies (baclofen and topiramate). We have developed information brochures on those approaches, conducted a treatment review, and are involved in evaluating these pharmacotherapies in various groups, such as those with comorbid depression and impaired drivers.
 
For more information please visit CAMH's Alcohol page.
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