University of Toronto
Medical Sciences Building, Room 4358
1 King's College Circle
Toronto, ON M5S 1A8
Dr. Susan George is Scientist and Head of Molecular Pharmacology in the Campbell Family Mental Health Research Institute at CAMH. She is a Professor of Medicine and Pharmacology at the University of Toronto. Dr. George is also a Tier 1 Canada Research Chair in Molecular Neuroscience.
Areas of Research
Dr. George studies how brain neurons communicate through neurotransmitters. The generation and control of intracellular signals is fundamental to the ability of cells to sense and respond to their environment. Her focus is on neuropsychiatric and addiction disease processes that are mediated by dopamine receptors and opioid receptors. She has discovered that these receptors play a novel role in brain disorders and drug dependency and therefore drugs active at these receptors may have therapeutic benefits. This has significant implications for understanding schizophrenia and drug addiction and provides new targets for designing medications for these conditions. Dr. George and her colleagues have also developed a novel drug screening assay that detects activators and blockers of G-protein-coupled receptors in a single, easy to set up format, which can also be used to visualize the dynamics of receptor oligomers in living cells in real time.
View Dr. George's publications on PubMed.